I am a MSTS fan, was going to be part of the beta for number 2 but looks like that fell through.
I have run the trainz program and I am sorry but when I have 10 mty cars and cant stop with full independent and full service then you can bet I am not going to be playing it too much.
But nothing ompares to the real thing.
Yes we are on time but this is yesterdays train
I do both.....
TRS-
If you like to make routes as its very easy to rather than it is a pain in the butt to do it in MSTS
If you like switching its a lot easier to do in here than in MSTS
MSTS
I use MSTS for just hauling trains from one side of town to the other side of town
Cabs and sounds are a lot better in MSTS than TRS
I am sure there is a lot more that others can name...But this is just a few that I can come up with