If by, "Scale wheels," you mean Proto-87 wheelsets, be aware that they are a LOT more sensitive to minor tracklaying irregularities (and commercial specialwork compromises) than RP-25 wheelsets. Also, if your track is built 'Proto-87 friendly' it may not be so friendly to RP25 wheels. As for cost, if you're converting from plastic or pizza cutters to quality metal wheelsets there may not be much difference. OTOH, if you have no reason to convert other than to get the (admittedly) better appearance...
Will it be worthwhile to convert? The only person who can answer that question for you is the one who ties your shoelaces.
Chuck (Modeling Central Japan in September, 1964)
Define Scale vs Commercial Wheelsets.
If you mean tread thickness, I've read that there could be issues with scale treads with some turnouts.
Springfield PA
This has probably been discussed before, but does anyone know, what the pros & cons, ins & outs of scale HO wheels versus commercial HO wheels are, including price?