I have 2 large main line loops, a 5 track engine yard, a reversing loop figure 8, a 12 siding, and 4 siding industrial area. I am running conventional, TMCC, DCS and Legacy. I have one new ZW with 2 power bricks, and the DCS AIU and 2 TIU's. The two main lines are powered by chanel A and D, this is done if I want to use the throttle handles. The engine yard is on Chanel B, and the siding, industrial area, and Figure 8 is on Channel C. I do have independent toggle switches at various locations so I can "shut off" different engines. I recommend Scotts Ckt Breakers, although I made my own. BTW the NEW ZW DOES have ckt breaker protection built in. But I wanted to be extra safe. With my setup I do have the TMCC Comand Ctr and have EITHER that or the Legacy connected. I run my accessories, layout lights, and Ross switches using the OLD ZW. (Also have home made ckt bkr box connected to it).
Should not be a problem with what you want to do.