Remember that the dream of adjusting power through 'just the right' combination of engines has been a will o'the wisp of designers -- wacky and good -- for many years. One of the express premises of the Baldwin Essl locomotive was that it could (more or less seamlessly, given the electrical connections) start and stop its 6000 nominal hp of power, in 750hp increments, depending on trailing load. This was 'not dissimilar' from the design premise of at least some of the gensets that only the necessary combustion power would be running at any given time, something probably of more interest to bureaucrats in places like SCAQMD or CARB, or bean-counting people responsible for fuel contracts, than actual railroaders trying to Run Trains.
Of course, in the late '30s, things like short-term pollution at start or restart, or mandatory long spoolup times for engine acceleration, would have been less significant. One thing about well-designed gensets was that they could share cooling loops, so if running on one engine, the other two could be kept at reasonable running temperature in the cooling jackets and engine structure and be more easily and less 'pollutingly' fired up; likewise the oil pressure on all the engines could be maintained, effectively as with a pre-lubing system, if any one engine were running, making it more practical to start, stop, and throttle them as "desired".
The great problem being that, as with the earlier generations of battery switcher, it appears that no one who understood how the locomotives would actually be used was involved in approving the final design.
One of the early comments I made to the Carnegie-Mellon 'integrated GIS' plan for autonomous fuel management was that it promised to make genset operation far more 'intuitive' to railroaders, as it could reasonably predict many types of increased power requirement and start and throttle-up engines as needed with less silly fribbling. Likewise, for flat switching there needed to be some 'advance' control, ideally of great simplicity, that when pulled would start the engines cycling on for maximal programmed acceleration and alert the engineer when 'ready' to be quickly loaded down. To my knowledge this was never implemented on the current range of gensets.
There are also potential issues with the source and design of the actual engines and 'gensets' used in these locomotives. To the extent they are sourced on OTR truck engines, with the vast wealth of horror literature regarding the smog equipment and expedient design (ahem, early-2000s Caterpillars?) in some generations of them, we could expect to see trouble x3 in a number of respects.
There have been a couple of other stabs at select-a-power in a single unit, the Cat PR43 being a particularly interesting example. This instead of having a buncha little prime movers had one big one, a C175 sized for 'average' use, and a little dozer-size C18 to be fired up either when higher peak horsepower or lower 'maintaining' horsepower was desired. If the cooling and oil systems were not interconnected, someone missed a stitch... particularly if an 'idle' or shut-down engine did not have hydrodynamic lubrication against road shock, something that might not be obvious to an OTR guy. This was an interesting and, to me, pretty-well-thought-out design -- but it does not seem to have caught on other than where PR30s were already in use.
In my opinion, a number of the design considerations used in the Budd RDCs (or the Essl locomotive) are (or ought to be) used on genset engines. Having the engine installation designed for easy maintenance is one; having the whole genset 'modular' for easy replacement without keeping the locomotive itself out of service is another. I of course would argue for using full SCR (with a little additional DEF to be paid for as for a fuel surcharge as an "environmental accommodation cost") for 100% of the NO reduction, thereby getting rid of the entire EGR boondoggle and perhaps the need for any sort of DPF kludge as well.
A proper battery/supercap hybrid gets rid of much of the 'predictive' issue with the genset instantaneous power accommodation, provided that someone who actually understands this type of power transmission has done the detail design. I am watching with great interest to see how the people in Fullerton manage to pull this off.