I do not have this software, but am taking a hard look at it. For $45.00 list price, you can pay it off by designing a couple of background buildings instead of buying a couple of Cornerstone background model kits.
A lot depends on what kind of printer you have. I have an Epson Stylus Photo R200 I bought at Staples. It is designed for printing photos as well as general printing. It has 6 cartriges, so when you run out of a color you just change that cartrige instead of throwing away a partially empty "color cartrige" where one of 3 internal colors has run dry. I have made a lot of signs with this printer, and that come out great. I use Epson Premium Glossy Photo Paper for the signs. I have also made decals with some sucess, but need more practice on this.
Someone asked about magazine reviews, their site references a number including MR, Classic Toy Trains, Scale Rails and others. There are also customer reviews in this page.
http://www.modeltrainsoftware.com/evdesore.html
The site also has a "Walk-Thru Video" of how the software works. From the looks, anyone who has done any graphics design, Photoshop, Powerpoint or similar software could jump into it easily.
http://www.modeltrainsoftware.com/mbvideo.html