Thanks for the feedback everyone. I had less time than I thought, but did manage to stop by The Toy Store. Unfortunately, they had only a small section of Lionel and MTH, and some G stuff as well. And no layout. Pricing was full retail.
I did hear about the Hobby House in Hendersonville, but just didn't have time to swing by there.
I have been to Smoky Mountain Trains before, and they have a GREAT O layout and museum if you're ever in the Bryson City area. You can also take a ride on the Great Smoky Mountain railroad while you're there.